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Chillsfevermuscle aches or painsnauseaor vomitingespecially if this happens with or shortly after a skin rashsigns of a serious allergic reactione.gabdominal crampsdifficulty breathingnausea and vomitingor swelling of the face and throatsigns of bleeding in the stomache.gbloodyblackor tarry stoolsspitting up of bloodvomiting blood or material that looks like coffee groundssigns of liver problemse.gnauseavomitingdiarrhealoss of appetiteweight lossyellowing of the skin or whites of the eyesdark urinepale stoolssigns of a severe skin reaction such as blisteringpeelinga rash covering a large area of the bodya rash that spreads quicklyor a rash combined with fever or discomfort.

Due to the occasional occurrence of drowsinesspatients should be alerted to the need for due precaution when engaging in activities where alertness is mandatory.

Since other medications may interact with allopurinoltell your doctor about all prescriptionnon-prescriptionillegalrecreationalherbalnutritionalor dietary drugs you are takingespeciallyAzathioprineImuranChlorpropamideDiabineseCyclosporineGengrafSandimmuneNeoralMercaptopurinePurinetholAntibiotics such as ampicillinPrincipenOmnipenothersor amoxicillinAmoxilAugmentinTrimoxWymoxBlood thinners such as warfarinCoumadinDiureticswater pills)

An interaction between two medications does not always mean that you must stop taking one of themSpeak to your doctor about how any drug interactions are being managed or should be managed.

Zyloprim SHOULD BE DISCONTINUED AT THE FIRST APPEARANCE OF SKIN RASH OR OTHER SIGNS WHICH MAY INDICATE AN ALLERGIC REACTIONIn some instances a skin rash may be followed by more severe hypersensitivity reactions such as exfoliativeurticarialand purpuric lesionsas well as Stevens-Johnson syndromeerythema multiforme exudativumand/or generalized vasculitisirreversible hepatotoxicityandon rare occasionsdeath.

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